Having spent a fair amount of time in my permanent assignment as an engineer in Chrysler's fuel systems lab in Highland Park, Michigan, I had the opportunity to evaluate especially the Carter and Holley brands of carburetors and knew both of the reps from those companies stationed directly in our lab on a full time basis. The Carter rep was Jim Pettis and the Holley one was Gary Congden who were both good friends of mine and I went out to lunch with both of them on a regular basis.
From my perspective and experience with both of those manufacturers, it was clear to me that at least when new, Holley carburetors just had more quick and uniform throttle response than the Carters, especially off the line and part throttle that gave a better performance feel overall. The Holley 4 bbls in the early 70s were especially excellent performers when new.
Their Achilles Heel though was that they were much more complex than the Carter 4 bbls for example with some intricate metering blocks in the center of the carburetors and they were also especially heavy units in comparison to the Carter AFB, AVS, etc models and therefore were more expensive to manufacture. So given the need to compete with the more simple and lighter Carter carburetors, Holley resorted to using casting materials that were not durable over time and more easily warped, both the 2 bbls and the 4 bbls. I was a student engineer in 1969 and 1970 and as such was able to afford getting a newer vehicle finally in 1972 and found my avatar car 1970 Chrysler 300 coupe as pictured at left on a Birmingham Chrysler-Plymouth used car lot and bought it on the spot - I just loved the colors on that car. Having only 29K miles on it, I was able to enjoy that car a lot but never used it in the snow back there and drove a beater 4 door 1966 Plymouth Fury sedan as my "salt car".
Anyway, after accumulating some 50K miles on the 300, my Holley 4 bbl started giving me problems so I tore it down and rebuilt it with a new carburetor kit, but that didn't help at all. So I asked Gary about it and he immediately told me to sit down and wait a minute and he brought out of the storeroom a brand new one (a 4160 model I believe it is). He said "here is your only real solution". He well knew the issue and I expect that is why the company no longer used that 4 bbl more than another year as I recall and then the Carter 4 bbls were the only 4 bbl. option on the V8s (the Carter Thermoquad 4bbls with their plastic fuel bowls also created some problems though).
My avatar car now has 205K miles on it and the drivetrain was pretty much rebuilt not too long ago - it is my favorite car of all time, although the 71s are just as desirable to me with a little better interiors in them. I mention this because Gary's assigned car that he got to select was a 1971 Chrysler 300 coupe in Tahitian Walnut and we went to lunch in it regularly that year - that car to me was just perfect in every way, both styling and engineering and that is why I have so many of them now - crazy