I put a Torker 383 on my '67 Newport 383 4bbl and the side-to-side rear a/c compressor bracket fit just like it did with the OEM 4bbl manifold. The mounting "ears" on the front of the manifold (front manifold bolts) are the same thickness as the OEM manifold's "ears". I would suspect your Edelbrock would be similar.
But DO compare the thickness of those front mounting ears before you pull things apart, for good measure.
Might have more issues getting the carb/kickdown linkage to work right. Edelbrock used to have an extension for the kickdown rod, which goes between the existing kickdown rod and the slotted end that screws onto it. Kind of like an extension "bushing" of sorts, female threads on one end and male threads on the other. But then I replaced the OEM AFB with a TQuad, so you might not need it.
Enjoy!
CBODY67