I've purchased several vehicles sight unseen, including three that I have now. It takes a little judgement on human nature when communicating with the sellers. An honest seller will usually down talk when questioned about spicifics, Or tell the truth if he dosen't know.
I've walked away from several also based on sketchy descriptions or lack of desire to comply with inspection/photo requests. But the vehicles i've followed up with a purchase have all been a pleasent experience. There has always been some aspect of the vehicle that was a dissapointment but nothing that would have been a deal killer with a personal inspection.
My 64 Dodge crewcab was purchased unseen by me, and I drove it 2200 miles home. Both the 65 Coronet 500 convertible and the 69 300 convertible were transported, even with that extra expense they both were excellent examples for my investment.