My 2c worth is that while the engine/trans combo could be had cheap,the engineering to make it work would be very time consuming and costly even if you can fabricate a bunch of it yourself.
I'm thinking motor/transmission mounts,aftermarket rad,complete fuel system with a pump in the tank,probably custom headers (big $$) and exhaust,steering linkage mods(?),tranny linkage of some sort,PS and A/C (?) plumbing issues,custom driveshaft,plus getting the electronics to work.
There's a couple guys on FABO that have swapped them into A-bodies so you could check out their threads on there for more info.
You have to ask yourself how much time/patience/ability you really have to make that all happen and will it be worth it in the end.A well built 440 will make similar power with no other changes necessary except a basic engine swap that you could do in a weekend.If you want to get better than OEM drivability and mileage then go with an aftermarket fuel injection and ignition system which are almost plug and play these days.
Personally,I really like the LS motors and have the 5.3 in my personal vehicle (05 Express Van) which is great as I use it for hauling,towing,as well as a camper van in the warmer months.